Genomic Oncology Education

Applying precision medicine approach to metastatic castration-resistant prostate cancer: urgent education need on genomic oncology

Metastatic castration-resistant prostate cancer (mCRPC) remains a therapeutic challenge. As a result of advances in genomic sequencing technology, “next-generation sequencing” (NGS) is increasingly incorporated into clinical trials and routine oncology clinical practice. Molecular profiling of mCRPC can be a valuable way of defining molecular alterations that might contribute to optimal treatme...

Oncology nursing education: teaching strategies that work.

Faculty at a university school of nursing developed an innovative oncology nursing elective designed to enhance baccalaureate students' knowing and aesthetic appreciation of persons living with cancer. Following completion of the course, students rank ordered class activities they felt would help them most in their nursing careers. Students chose the cancer survivor interview first, followed by...

Genomic-Wide Analysis with Microarrays in Human Oncology

DNA microarray technologies have advanced rapidly and had a profound impact on examining gene expression on a genomic scale in research. This review discusses the history and development of microarray and DNA chip devices, and specific microarrays are described along with their methods and applications. In particular, microarrays have detected many novel cancer-related genes by comparing cancer...

Genomic Expression Profiles: From Molecular Signatures to Clinical Oncology Translation

Resources for Interpreting Variants in Precision Genomic Oncology Applications

Precision genomic oncology-applying high throughput sequencing (HTS) at the point-of-care to inform clinical decisions-is a developing precision medicine paradigm that is seeing increasing adoption. Simultaneously, new developments in targeted agents and immunotherapy, when informed by rich genomic characterization, offer potential benefit to a growing subset of patients. Multiple previous stud...